apalutamide will decrease the level or outcome of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medications which can be CYP3A4 substrates can result in lower publicity to these medications.nelfinavir will increase the stage or effe

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